|Synonyms:||2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-4,8,9-triol deriv. Hydrobromide; Acetyl-10-deoxysepaconitine Hydrobromide|
·Lappaconitine hydrobromide is a selective blocker of the TTX-sensitive Na+ channels, and does not influence the activation threshold of Na+ channels.
·Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
·Lappaconitine hydrobromide is a diterpene alkaloid extracted from roots of Aconitum sinomantanum. It is a non-narcotic central nervous system analgesic. Lappaconitine also has antiarrhythmic and anti-inflammatory effect. Lappaconitine works as an inhibitor of tetrodotoxin-sensitive, voltage-dependent sodium channels. On the other hand, lappaconitine is reported as an organocatalyst for asymmetric α-hydroxylation of β-keto esters.
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Zhengzhou Sigma Chemical Co., LTD. is located in the central area of China--Zhengzhou City, Henan Province. It is a complex enterprise which integrates scientific research, production and trade. Zhengzhou Chemical Chem Co., Ltd., a Hi-tech enterprise, subordinates to it. It has the advanced R&D center, modernizational inspection center, standardized GMP workshop, large scale production base and informationalized trade group.
The main products of Zhengzhou Sigma Chemical Co., LTD. are: advanced chemicals, such as Esomeprazole magnesium/sodium, Entecavir, Voglibose, Rifamycin sodium, Decaborane, Chlorodimethylphenylsilane, 9-Oxo-10 (9H)-acridine acetic acid and acridine series, [2,2':6',2''-Terpyridine]-4,4',4''-tricarboxylicacid and pyridine series, 2-(Tributylstannyl) pyridine, Tributyl(vinyl)tin and Tin products series, 4-Bromine-2-indole ketone and derivatives, 9,9-Dimethyl-2-iodofluorene fluorene and its series and so on;
Cyanidation---Bromination---Catalytic hydrogenation---Chlorination---Diazotation---Friedel crafts reaction
Grignard reaction---Hoffman reaction ---Hydroformylation---Isomerisation---Methylation with methyl bromide
Nitration---Oxidation---Phosgenation---Resolution of racemates---Low temperature reaction (-80 deg c)
High temperature and pressure reaction
At present, with the high quality products and best services, our market has arrived in more than 30 countries and regions, such as U.S.A., England, Canada, Russia, Spain, Turkey, Argentina, Egypt, Vietnam, Bangladesh, Pakistan, South Africa etc..
“Unite, exceed, share and win” is our central management idea. We will always focus on establishing a team with the most cohesive force, creativity and the ability of offering high quality services. We will be willing to share our products, knowledge, innovation, and experience with our team and colleagues. We will try to take the projects, products and services we commonly admire to achieve our common goals.
Sigma people sincerely welcome the consultations, negotiations and cooperation!